basic FUNCTION
| lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation |
|
playing a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids |
|
also acting as a phenylpyruvate tautomerase, and additional role in integrin signaling pathways |
|
catalyzes the tautomerization of d-dopachrome methyl ester |
|
involved in the regulation and having different roles in the reparative, reproductive and inflammatory-like processes occuring in endometrium during every menstrual cycle |
|
plays an important role in acute and chronic inflammatory diseases such as septic shock, rheumatoid arthritis and colitis |
|
essential and crucial role in cell proliferation and the cell cycle |
|
may regulate the pro-apoptotic activity of BCL2L11 and inhibit the release of cytochrome c from mitochondria |
|
plays a complex role in malarial pathogenesis |
|
chemokine-like inflammatory mediator that triggers leukocyte recruitment by binding to CXCR2 and CXCR4 |
|
proinflammatory cytokine secreted by activated T cells and macrophages that has antiapoptotic, proproliferative, and chemotactic effects |
|
potential skeletal muscle cytokine with probable functions beyond inflammatory pathology in the complex regenerative response to muscle fiber damage |
|
with SOD2 appear to be early predictors for survival in septic patients |
|
key proinflammatory mediator, which plays a pivotal role in inflammatory and immune diseases |
|
important factor responsible for early polymorphonuclear cell activation and can be a target of immunomodulation after injury |
|
promotes leukocyte recruitment to sites of inflammation |
|
MIF and CD74 play previously unappreciated roles in CCL2-induced macrophage adhesion and migration, and they indicate that MIF and CD74 mediate this effect via both common and independent mechanisms |
|
MIF and its receptor, CD74, are involved in regulating the migration of human mesenchymal stem cells (MSCs |
|
is a major bioactive component of the previously uncharacterized otocyst-derived factor, which directs initial neurite outgrowth from the statoacoustic ganglion (SAG) to the developing inner ear |