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FLASH GENE
Symbol LSR contributors: mct - updated : 10-04-2013
HGNC name lipolysis stimulated lipoprotein receptor
HGNC id 29572
Location 19q13.13      Physical location : 35.739.558 - 35.758.865
Synonym name
  • liver-specific bHLH-Zip transcription factor
  • LISCH protein
  • lipolysis-stimulated remnant
  • liver-specific bHLH-Zip transcription factor
  • Synonym symbol(s) LISCH7, LISCH,MGC10659, MGC48312, MGC48503
    DNA
    TYPE functioning gene
    STRUCTURE 19.00 kb     10 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 2228 - 630 - -
    - - 2285 71 649 - -
    - - 2081 - 581 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • cytoplasmic domain of LSR was responsible for the recruitment of MARVELD2
  • HOMOLOGY
    Homologene
    FAMILY
  • immunoglobulin superfamily
  • LISCH7 family
  • CATEGORY transcription factor , receptor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • tTJ (Tricellular tight junctions) -associated membrane protein
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • LSR-MARVELD2 system plays a key role in tight junctions formation
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • defines tricellular contacts in epithelial cellular sheets by acting as a landmark to recruit MARVELD2 for tTJ formation
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS