basic FUNCTION
| may be playing a role in X-linked gene expression |
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is responsible for the majority of tetramolecular G4-DNA resolvase activity |
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fourth RNA helicase detected in stress granules (SGs), after DDX6, DDX3, and EIF4A, and its association with SGs is dynamic and mediated by an DHX36-specific RNA-binding domain |
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its helicase activity is sufficient to unwind the quadruplex and promote an interaction with 25 internal nucleotides to form a stable P1 helix |
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is the only helicase having G-quadruplex (G4)-RNA resolvase activity and the major source of G4-DNA resolvase activity |
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may potentially play a role in the regulation of gene expression that relies on its G4 resolvase activity |