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FLASH GENE
Symbol ZNF266 contributors: npt - updated : 04-05-2009
HGNC name zinc finger protein 266
HGNC id 13059
Location 19p13.2      Physical location : 9.523.271 - 9.546.234
Synonym name zinc finger protein 1
Synonym symbol(s) HZF1, KIAA2007
DNA
TYPE functioning gene
STRUCTURE 22.96 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
text structure 4 exons coding
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 3618 62 549 - Peng (2006)
- - 3338 62 549 - Peng (2006)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticmonocyte
Lymphoid/Immunemacrophage
cell lineage
cell lines monoblast cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a zinc finger domain
  • a nuclear localization signal (NLS)
  • an Asp-Glu and a Ser-Arg rich regions
  • a zinc coordinating DNA binding domain
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • potential regulator of transcription and/or splicing
  • involved in the regulation of cell morphogenesis or cell identity
  • CELLULAR PROCESS nucleotide, transcription, maturation
    nucleotide, transcription, regulation
    cell organization/biogenesis
    PHYSIOLOGICAL PROCESS development
    text hematopoiesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS