basic FUNCTION
| playing an important role for both mitochondrial function and early neuronal development |
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complexing with TIMM23 |
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TIMM50, as a receptor, is essential for precursor proteins to be imported into the mitochondrial matrix |
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involved in protein translocating into the inner mitochondrial membrane |
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new role for TIMM50 in regulating cell proliferation and apoptosis through decreasing mitochondrial membrane potential in breast cancer cell |
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is an important biomarker for mitochondrial dysfunction, in particular for mitochondrial membrane defects |
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is a major receptor for transporting the precursor protein across the mitochondrial inner membrane in TIM23 complex |
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role of TIMM50 in the regulation of oxidative stress and cardiac morphology |
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could attenuate pathological cardiac hypertrophy primarily by reducing oxidative stress |