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FLASH GENE
Symbol SLC35A1 contributors: npt/ - updated : 28-09-2004
HGNC name solute carrier family 35 (CMP-sialic acid transporter), member A1
HGNC id 11021
Corresponding disease
CDG2F congenital disorder of glycosylation, type 2F
Location 6q15      Physical location : 88.182.642 - 88.222.051
Synonym name
  • solute carrier family 35 (UDP-galactose transporter), member 1
  • mutated CMP-sialic acid transporter A1
  • Synonym symbol(s) CST, CMPST, FLJ76955, CMP-Sia-Tr, CMP-SA-Tr
    DNA
    TYPE functioning gene
    STRUCTURE 39.42 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1741 - 278 - -
    8 - 1918 - 337 - -
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestiveliver    
    Endocrinepancreas    
    Nervousbrain    
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES Hydrophobic
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies ortholog to murine Slc35a1
    homolog to Drosophila Csat
    homolog to C.elegans ZK370.7
    intraspecies homolog to SLC35A2
    Homologene
    FAMILY
  • nucleotide-sugar transporter family
  • SLC35A subfamily
  • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • transporting CMP-sialic acid from the cytosol into golgi vescles where glycosyltransferases function
  • CELLULAR PROCESS protein, post translation
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text CMP-sialic acid transport ; nucleotide-sugar transport
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) CDG2F
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS