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FLASH GENE
Symbol CEACAM5 contributors: - updated : 01-07-2006
HGNC name carcinoembryonic antigen-related cell adhesion molecule 5
HGNC id 1817
Location 19q13.2      Physical location : 42.212.529 - 42.234.436
Synonym name meconium antigen 100
Synonym symbol(s) CEA, CD66e
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 21.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Map see CEA@
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
 mouthtongue   
 stomach    
Endocrinepancreas   moderately
Respiratorylung   moderately
 respiratory tracttrachea   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines adenocarcinomas of endodermally derived digestive system epithelium and fetal colon
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven immunoglobulin-like domains
conjugated GlycoP
HOMOLOGY
intraspecies homolog to carcinoembryonic antigen
Homologene
FAMILY
  • immunoglobulin superfamily
  • CEA subfamily
  • CATEGORY adhesion , antigen
    SUBCELLULAR LOCALIZATION     plasma membrane
    text attached to the membrane by a GPI-anchor
    basic FUNCTION acting as a tumor antigen
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component complex immunoreactive glycoprotein of 180 kDa comprising 60% carbohydrate
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS