basic FUNCTION
| having a motor activity |
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conforms to a sarcomeric motor consensus, which suggests it has a unique function relative to the nonmuscle isoforms expressed in neurons |
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maintains synaptic strength in hippocampal neurons through an actin-dependent mechanism |
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MYH7B and MYH10 have distinct and overlapping effects on spine morphology |
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is necessary for steady-state synaptic transmission in hippocampal neurons |
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MYH7B and MYH15 play a prominent role in the heart and skeletal muscles of certain species like chicken and snakes, whereas in mammals, the only muscles that these myosin motors function in are highly specialized muscles |
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may have a role that uniquely fits a contractile requirement of the specialized muscles |
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expression of MYH7b protein in the mammalian heart has been inhibited during the evolution of mammals most likely to prevent the development of a severe cardiomyopathy that is sexually dimorphic |