basic FUNCTION
| may be having a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse |
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exhibits Ca(2+)-dependent phospholipid-binding activity through its C2A domain, and the Ca(2+)-binding activity is thought to be important for the regulation of Ca(2+)-dependent exocytosis |
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DOC2A, DOC2B are modulators of spontaneous synaptic transmission that act by a Ca(2+)-independent mechanism |
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specifically modulates the asynchronous phase of neurotransmitter release |
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emerges as a candidate Ca2+ sensor that might function to trigger asynchronous exocytosis in neurons |
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slow Ca2+ sensor that plays a critical role in asynchronous neurotransmitter release |
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regulates Ca2+-dependent spontaneous synaptic vesicle (SV) fusion events |
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DOC2A, DOC2B functions as Ca2+ sensors for slow asynchronous SV exocytosis in hippocampal neurons |