Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | DGKD | contributors: mct - updated : 02-09-2014 |
HGNC name | diacylglycerol kinase, delta 130kDa |
HGNC id | 2851 |
|
Location | 2q37.1 Physical location : 234.263.152 - 234.380.743 |
Synonym name | |
| |
Synonym symbol(s) | DGKdelta, KIAA0145, dgkd-2 |
EC.number | 2.7.1.107 |
DNA |
TYPE | functioning gene |
STRUCTURE | 117.60 kb 30 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
---|
EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cell lineage
cell lines
| tumor cell lines | fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
| |
| |
|
mono polymer | homomer , octamer |
HOMOLOGY |
interspecies | homolog to murine Dgkd |
Homologene |
FAMILY | eukaryotic diacylglycerol kinase family |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm |
basic FUNCTION | |
| |
| |
| |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | signal transduction |
a component | heterodimerizing with DGK |
INTERACTION |
DNA |
RNA |
small molecule | |
protein |
cell & other |
REGULATION |
induced by | phorboester (isoform 2) |
Other | suppressed by phorboester (isoform 1) |
polymerization of DGKD regulates the activity of the enzyme by sequestering DGKD in an inactive cellular location |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
|
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |