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FLASH GENE
Symbol CPNE6 contributors: npt/ - updated : 06-02-2008
HGNC name copine VI (neuronal)
HGNC id 2319
Location 14q11.2      Physical location : 24.540.755 - 24.547.295
Synonym name
  • neuronal copine
  • copine 6
  • Synonym symbol(s) N-COPINE
    DNA
    TYPE functioning gene
    STRUCTURE 6.54 kb     17 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    17 - 2018 62 557 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbraindiencephalonhypothalamus  
    Olfactoryolfactory bulb    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Nervousneuron
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two Ca(2+)- and phospholipid-binding domains known as 'C2 domains'
  • a C terminal region distantly to the A domain
  • one WWFA domain
  • HOMOLOGY
    Homologene
    FAMILY
  • copine family
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    text cell bodies dendrites
    basic FUNCTION
  • calcium-dependent, phospholipid binding protein, potentially involved in regulating membrane trafficking and in protein-protein interactions
  • synaptic plasticity
  • memory formation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text vesicular transport, membrane trafficking
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
  • phospholipid
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS