protein
| the C-terminal region of beta-catenin (CTNNB1) |
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interacts with polycystin-2/PKD2 and GOLGA2 |
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C8orf4 interacts with Chibby (CBY1) and thereby enhances the signaling pathway by relieving the antagonistic function of CBY1 on the beta-catenin-mediated transcription |
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cooperates with 14-3-3 adaptor proteins to facilitate nuclear export of beta-catenin, following phosphorylation of CBY1 by AKT1 kinase |
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physically interacts with the key downstream coactivator beta-catenin and represses its transcriptional activation potential |
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combinatorial action of CBY1 and 14-3-3 proteins controls the dynamic nuclear-cytoplasmic trafficking of beta-catenin |
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repressor of Wnt signaling, interacting with multiple NBPF proteins (NBPF1) (a coiled-coil region in the NBPF proteins interacts with the coiled-coil domain in the C-terminal region of CBY1) |
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direct downstream target for the master ciliogenesis transcription factor FOXJ1 |
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CBY1 plays a role in the proper distribution of IFT particles to preserve normal ciliary morphology in airway ciliated cells |
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CIBAR1, and CIBAR2 interact with CBY1 to promote ciliogenesis via regulation of membrane-remodeling processes |
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CEP164 is necessary for the proper recruitment of another distal appendage/transition fiber protein Chibby1 (CBY1) and its binding partners FAM92A and FAM92B to the ciliary base in multiciliated cells |
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DZIP1L interacts with, and acts upstream of, CBY1, an appendage protein, in ciliogenesis |