basic FUNCTION
| playing a role in protein-protein interactions and signal transduction |
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playing a role in hibernoma pathogenesis |
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may be involved in platelet-endothelium interactions |
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highly specific molecule for activated Tregs (T regulators), which could play an important role in their identification and function (Wang 2009) |
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might bind and anchor latent TGFB and is critical for the surface expression of latent TGFB by binding to the complex and functioning as its cell surface receptor (Tran 2009) |
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involved in the important pathway of TGFB regulation of morphogenesis, immune homeostasis, inflammation, and tissue remodeling (Tran 2009) |
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essential molecule for mesenchymal stromal cells (MSCs) biology, regulating their immunomodulatory and proliferative activities |
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soluble GARP acting likely as immune modulator |
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involved in TGFB1 activation by regulatory T cells (Treg), a subset of CD4+ T lymphocytes specialized in suppression of immune responses |
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LRRC32 expression on immune and non-immune cells is involved in maintaining peripheral tolerance, and it plays an important role in preventing inflammatory diseases such as allergy and graft versus host disease |