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FLASH GENE
Symbol AP3M1 contributors: mct/npt - updated : 10/09/2008
HGNC name adaptor-related protein complex 3, mu 1 subunit
HGNC id 569
Location 10q22.2      Physical location : 75.880.015 - 75.910.826
Synonym name
  • AP-3 adapter complex mu3A subunit
  • Mu-adaptin 3A
  • Mu3A-adaptin
  • clathrin adaptor complex AP3, mu-3A subunit
  • Synonym symbol(s) MGC22164
    DNA
    TYPE functioning gene
    STRUCTURE 30.82 kb     9 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 5270 46 418 - Drake (2000)
    9 - 5144 46 418 - Drake (2000)
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestine   highly
    Nervousbrain   highly
    Reproductivemale systemtestis  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer heteromer , tetramer
    HOMOLOGY
    Homologene
    FAMILY
  • adaptor complexes medium subunit family
  • CATEGORY adaptor , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • having functions in cargo-selective transport of proteins from the Golgi to the lysosome
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component subunit of the AP3 complex
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS