Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | SP100 | contributors: mct - updated : 12-06-2013 |
HGNC name | nuclear antigen SP100 |
HGNC id | 11206 |
|
Location | 2q37.1 Physical location : 231.280.870 - 231.410.317 |
Synonym name | speckled, 100kD |
Synonym symbol(s) | LEU5, RFP2, LYSP100B |
DNA |
TYPE | functioning gene |
STRUCTURE | 129.45 kb 25 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
---|
text | three variants SP100, SP100B, SP100.HMG.1 (chimeric fusion between SP100 and a HMG1-like peptide) |
EXPRESSION |
Type |
expressed in | (based on citations) |
organ(s) |
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
mono polymer | homomer , dimer |
HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | regulatory , transcription factor |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm | |
intracellular,nucleus,nucleoplasm,nuclear bodies,PML | |
intracellular,nucleus,nucleolus | |
text | |
|
basic FUNCTION | |
| |
| |
| |
| |
| |
|
CELLULAR PROCESS | nucleotide, transcription |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
| |
| |
|
cell & other |
REGULATION |
Other | degraded in a proteasome-dependent manner at late times postinfection, suggesting that SP100 may play an additional antiviral role during the late phase |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
|
Susceptibility |
Variant & Polymorphism
other
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |