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FLASH GENE
Symbol CEPT1 contributors: mct/npt - updated : 23-08-2007
HGNC name choline/ethanolamine phosphotransferase 1
HGNC id 24289
Location 1p13.2      Physical location : 111.682.248 - 111.727.724
Synonym name
  • choline/ethanolaminephosphotransferase
  • CDP-ethanolamine:diacylglycerol ethanolaminephosphotransferase
  • Synonym symbol(s) MGC45223, DKFZp313G0615
    EC.number 2.7.8.1, 2.7.8.2
    DNA
    TYPE functioning gene
    STRUCTURE 45.50 kb     9 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map pter - D1S2235 - D1S2809 - CEPT1 - D1S2789 - D1S2837 - cen
    RNA
    TRANSCRIPTS type messenger
    text variants 1 and 2 encode the same protein
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    9 - 2213 46.4 416 - -
    9 - 2251 46.4 416 - -
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a predicted amphipathic helix within the active site with the final two ASP residues of the CDP-alcohol phosphotransferase motif
  • HOMOLOGY
    intraspecies paralog to CEPT1
    Homologene
    FAMILY
  • CDP-alcohol phosphatidyltransferase class-I family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    basic FUNCTION
  • synthesis of phosphatidylethanolamine and phosphatidylcholine
  • catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine (PE)(Horibata 2007)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS