basic FUNCTION
| antiangiogenic factor, expressed abundantly in the elastin-rich subendothelial outer layer (Kimura 2008) |
|
may play a role in adipose tissue function (Saiki 2009) |
|
inhibits angiogenesis in adipose tissue, but could have metabolic effects in addition to its role in angiogenesis (Saiki 2009) |
|
with scleraxis (SCX), TNMD is a candidate marker gene for tenocytes |
|
acts on the maturation or maintenance of the periodontal ligament (PDL) by positively regulating cell adhesion via its BRICHOS domain |
|
acts as a protective factor in visceral adipose tissue to alleviate insulin resistance in obesity |
|
specific marker of tendons and ligaments |
|
is required for proper tendon tissue adaptation to endurance running |
|
WNT/CTNNB1 decreased MKX and TNMD expressions without suppressing SCX expression in SCX-programmed tendon progenitors |
|
important for tendon maturation, running performance and has key implications for the resident tendon stem/progenitor cells (TSPCs) |
|
is required for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing |