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FLASH GENE
Symbol CHRFAM7A contributors: - updated : 25-09-2006
HGNC name CHRNA7 (cholinergic receptor, nicotinic, alpha polypeptide 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
HGNC id 15781
Location 15q13-q14      Physical location : 30.653.442 - 30.685.864
Synonym symbol(s) D10, CHRNA7-DR1
DNA
TYPE breakpoint
SPECIAL FEATURE opposite orientation
text opposite orientation with CHRNA7
STRUCTURE 32.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map cen - FAM7A1 - CHRFAM7A - D15S165 - D15S976 - D15S1013 - D15S1031 - D15S1360 - CHRNA7 - ARHGAP11A - D15S1010 - qter
Authors de Riley (02)
RNA
TRANSCRIPTS type untranslated transfer
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2858 - 412 - Freedman
- - 2794 - 321 - Freedman
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineparathyroid   highly
 thyroid    
Reproductivemale systemtestis   
Urinarybladder    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY ligand-gated ionic channel (TC 1.A.9) family
CATEGORY
SUBCELLULAR LOCALIZATION     plasma membrane
text postsynaptic membrane
basic FUNCTION forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A)
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral        
in psychosis
Susceptibility to psychosis
Variant & Polymorphism other a polymorphic 2 bp deletion within exon 6 in psychosis
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS