basic FUNCTION
| inhibiting signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form |
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inhibits CREB-dependent transcription of target genes through disruption of complexes formed at the promoter |
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restricts certain GPCR-mediated biological responses of human mast cells |
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scaffold that control diverse signaling pathways by modulating signalosome formation and by accelerating the GTPase activity of heterotrimeric G protein |
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inhibited cyclic AMP-dependent protein kinase (PKA)-induced gene expression through interactions with the transcription factor cAMP-response element-binding (CREB1) protein |