Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | GCLM | contributors: - updated : 26-04-2006 |
HGNC name | glutamate-cysteine ligase, modifier subunit |
HGNC id | 4312 |
|
Location | 1p22.1 Physical location : 94.352.589 - 94.375.012 |
Synonym name | glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD) |
Synonym symbol(s) | GLCLR |
EC.number | 6.3.2.2 |
DNA |
TYPE | functioning gene |
STRUCTURE | 20.00 kb 7 Exon(s) |
Genomic sequence alignment details |
---|
10 Kb 5' upstream gene genomic sequence study |
regulatory sequence | Promoter |
Binding site | |
text structure | an antioxidant response element (ARE) and a 44-bp fragment upstream of the ARE,including a consensus AP-1 site previously considered responsible for the enhancer activity of the upstream fragment. |
MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
---|
EXPRESSION |
Type | ubiquitous |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
mono polymer | heteromer , dimer |
HOMOLOGY |
Homologene |
FAMILY | |
|
CATEGORY | regulatory |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria |
basic FUNCTION | |
|