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FLASH GENE

Symbol

PHF10

contributors: np/ - updated : 16-01-2007

HGNC name	PHD finger protein 10
HGNC id	18250

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	6q27      Physical location : 170.104.003 - 170.124.106
Synonym name	BRG1-associated factor, 45-KD, A
	PHD zinc finger protein XAP135
Synonym symbol(s)	FLJ10975, XAP135, MGC111009, BAF45a

DNA

TYPE	functioning gene
STRUCTURE	20.11 kb     12 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_018288 12 - 1692 NP_060758 - 498 - 2002 11827455 NM_133325 12 - 1686 NP_579866 - 496 - 2002 11827455

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine adrenal gland         Nervous brain diencephalon hypothalamus       brain forebrain cerebral cortex       ganglia sensory ganglia dorsal root     Reproductive female system uterus         male system prostate

cells

System Cell Pubmed Species Stage Rna symbol Nervous neuron

cell lineage
cell lines	gastric cancer cell lines
fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

two PHD zinc fingers

HOMOLOGY

Homologene

FAMILY	the REQUIEM/D4 family
	SAYP family

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm
	intracellular,nucleus

basic FUNCTION

may be having an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor

CELLULAR PROCESS

nucleotide, transcription

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS