Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | FOLR3 | contributors: mct - updated : 27-12-2017 |
HGNC name | folate receptor 3 (gamma) |
HGNC id | 3795 |
|
Location | 11q13.4 Physical location : 71.846.770 - 71.850.934 |
Synonym symbol(s) | FRG, FR-G, FR-gamma, gamma-hFR |
EC.number | 3.1.3.11 |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | component of a cluster |
STRUCTURE | 4.18 kb 5 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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text structure | Sp1 and ets binding elements exist in proximal promoter for transcriptional activity |
MAPPING | cloned | Y | linked | status | provisional |
regionally located | telomeric of the FGF3 locus |
RNA |
TRANSCRIPTS | type | messenger |
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text | two isoforms produced by alternative splicing |
|
EXPRESSION |
Type |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cell lineage | hematopoietic |
cell lines | ovarian and uterine carcinomas |
fluid/secretion |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| twenty three AA signal peptide,sixteen conserved cysteine residues,three potential N linked glycosylation sites |
secondary structure | eight disulfide bonds |
conjugated | GlycoP |
HOMOLOGY |
interspecies | homolog to C.elegans F17B5.5 |
intraspecies | homolog to FOLR1,FOLR2 |
Homologene |
FAMILY | folate receptor family |
CATEGORY | transport |
SUBCELLULAR LOCALIZATION | extracellular |
plasma membrane | |
intracellular,cytoplasm,organelle,lumen | |
intracellular,cytoplasm,cytosolic,granule | |
text | secreted and GPI membrane anchored |