protein
| complex striatin-interacting phosphatase and kinase (STRIPAK), can establish mutually exclusive interactions with the cortactin-binding proteins cortactin-binding protein 2 (CTTNBP2)/cortactin-binding protein 2, N-terminal-like (CTTNBP2NL) or with an assembly of sarcolemmal membrane-associated protein (SLMAP) |
|
CTTNBP2 modulates the mobility of cortactin in neurons |
|
interacts with cortactin to regulate cortactin mobility and control dendritic spine formation |
|
in addition to spine morphology, CTTNBP2 is also found to regulate the synaptic distribution of striatin and zinedin |
|
CTTNBP2 targets the PP2A complex to dendritic spines |
|
interactions of CTTNBP2 and cortactin and the PP2A complex regulate spine morphogenesis and synaptic signaling |