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FLASH GENE
Symbol SLC13A4 contributors: mct - updated : 28-02-2014
HGNC name solute carrier family 13 (sodium/sulfate symporters), member 4
HGNC id 15827
Location 7q33      Physical location : 135.365.992 - 135.412.933
Synonym name sulphate transporter 1
Synonym symbol(s) SUT-1, SUT1, hNaS2
DNA
TYPE functioning gene
STRUCTURE 46.00 kb     16 Exon(s)
10 Kb 5' upstream gene genomic sequence study
regulatory sequence Promoter (CAAT box)
cytosine-phosphate-guanine/HTF
Binding site   transcription factor
text structure 5'-flanking region contains CAAT- and GC-box motifs, and a number of putative transcription factor binding sites, including GATA-1, AP-1, and AP-2 consensus sequences
MAPPING cloned Y linked N status provisional
regionally located between markers D7S500 and D7S509
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Reproductivefemale systemplacenta    Homo sapiens
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text
  • most abundant sulfate transporter mRNAs, which localized to syncytiotrophoblast cells
  • PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to rattus Nasi-1
    Homologene
    FAMILY solute carrier family 13 (sodium/sulfate symporters)
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • sodium/sulfate cotransporter mediating sulfate reabsorption in the high endothelial venules
  • physiological roles for SLC13A4 and SLC26A2 in human placental sulfate transport
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS