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FLASH GENE

Symbol

AADAC

contributors: - updated : 08-04-2006

HGNC name	arylacetamide deacetylase (esterase)
HGNC id	17

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	3q21.3-q25.2      Physical location : 151.531.860 - 151.546.277
Synonym symbol(s)	DAC
EC.number	2.1.3.5

DNA

TYPE	functioning gene
STRUCTURE	14.00 kb     5 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

Map	cen - D3S1576 - D3S1309 - D3S1569 - AADAC - D3S1570 - D3S1270 - qter
Authors	Yamazaki (97)

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart         Digestive intestine small intestine         liver         Endocrine adrenal gland

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective adipose

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

intraspecies

homolog to hormone sensitive lipase

Homologene

FAMILY

"GDXG" lipolytic enzyme family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,membrane
	intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
	intracellular,cytoplasm,cytosolic,microsome
text	type II membrane protein

basic FUNCTION

playing an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

amine , drug

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS