Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol GPR85 contributors: mct/npt - updated : 23-06-2006
HGNC name G protein-coupled receptor 85
HGNC id 4536
Location 7q31      Physical location : 112.720.467 - 112.727.833
Synonym name
  • super conserved receptor expressed in brain 2
  • seven transmembrane helix receptor
  • Synonym symbol(s) SREB2, SREB
    DNA
    TYPE functioning gene
    STRUCTURE 7.00 kb     3 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 4965 42 370 - Matsumoto (2008)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrainbasal nucleicorpus callosum  
     brainlimbic systemhippocampusdentate gyrushighly
     spinal cord    
    Reproductivemale systemtestis   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectivebone   
    Nervouscentral   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • N linked glycosylation site in extracellular domain
  • conserved cysteine residues, forming a disulfide bridge in the first and second extracellular loops
  • HOMOLOGY
    interspecies homolog to zebrafish Sreb2
    Homologene
    FAMILY
  • rhodopsin family
  • G protein coupled receptor
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in determining brain size, modulating diverse behaviors, and potentially in vulnerability to schizophrenia
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS