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FLASH GENE

Symbol

MRS2

contributors: npt - updated : 22-12-2005

HGNC name	MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
HGNC id	13785

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	6p22.3-p22.1      Physical location : 24.403.152 - 24.425.809
Synonym name	MRS2-like, magnesium homeostasis factor (S. cerevisiae)
	magnesium transporter MRS2L, mitochondrial
	MRS2-like protein
Synonym symbol(s)	MRS2L, HPT, MGC78523

DNA

TYPE	functioning gene
STRUCTURE	22.00 kb     11 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed MRS2 11 - 3348 50 443 - -

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Lymphoid/Immune lymph node       highly Nervous brain forebrain cerebral cortex temporal cortex     brain diencephalon hypothalamus       brain diencephalon amygdala       brain forebrain cerebral cortex frontal cortex

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

two predicted transmembrane domains at C terminus (first terminated with the conserved motif F/Y-G-M-N)

HOMOLOGY

interspecies

homolog to yeast mitochondrial MRS2,Mpelo

Homologene

FAMILY

CORA family of magnesium transporter

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria,outer

basic FUNCTION

playing a role essential for mitochondrial function

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS