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FLASH GENE
Symbol TAS2R7 contributors: mct/npt - updated : 22-04-2009
HGNC name taste receptor, type 2, member 7
HGNC id 14913
Location 12p13.2      Physical location : 10.954.131 - 10.955.226
Synonym name
  • candidate taste receptor T2R7
  • taste receptor, family B, member 4
  • Synonym symbol(s) T2R7, MGC142121, TRB4
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text cluster interspersed with the proline rich protein cluster
    STRUCTURE 1.10 kb     1 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 1096 36.4 318 - Sainz (2007)
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivemouthtongue   
    digestivemouthpalate   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsensorygustatory  
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Gustatoryclear receptor cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • seven transmembrane segments (7TM) receptor
  • an extracellular lignand binding domain
  • HOMOLOGY
    interspecies ortholog to a bitter cluster on murine chromosome 6
    Homologene
    FAMILY
  • G protein coupled receptor superfamily
  • taste receptor (T2R) family
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in bitter perception
  • broadly tuned receptor responding to strychnine, quinacrine, chloroquine and papaverine (Sainz 2007)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction , sensory transduction/taste
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS