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FLASH GENE
Symbol TAS2R1 contributors: mct - updated : 05-01-2006
HGNC name taste receptor, type 2, member 1
HGNC id 14909
Corresponding disease
PROP phenylthiocarbamide sensitivity, testing, sensibility 2
Location 5p15.2      Physical location : 9.629.108 - 9.630.463
Synonym name
  • taste receptor, family B, member 7
  • candidate taste receptor T2R1
  • Synonym symbol(s) T2R1, TRB7
    DNA
    TYPE functioning gene
    STRUCTURE 0.00 kb     1 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Map see PROP
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivemouthtongue   
    digestivemouthpalate   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelial    
    Epithelialsensorygustatory  
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Gustatoryclear receptor cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • seven transmembrane segments (7TM) receptor
  • an extracellular ligand binding domain
  • HOMOLOGY
    Homologene
    FAMILY
  • G protein coupled receptor superfamily
  • taste receptor family
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    text selectively in taste receptor
    basic FUNCTION
  • involved in bitter perception
  • utilized to recognize and perceive the structure and bitterness of peptides
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction , sensory transduction/taste
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by bitter peptides
    ASSOCIATED DISORDERS
    corresponding disease(s) PROP
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS