Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | OAS1 | contributors: mct - updated : 11-04-2018 |
HGNC name | 2',5'-oligoadenylate synthetase 1, 40/46kDa |
HGNC id | 8086 |
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Corresponding disease |
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Location | 12q24.13 Physical location : 113.344.738 - 113.357.711 | ||
Synonym name | polynucleotide adenylyltransferase | ||
Synonym symbol(s) | E18/E16, OIAS1, IFI4, IFI-4, OIAS | ||
EC.number | 2.7.7.19/ 2.7.7.84 |
DNA |
TYPE | functioning gene |
STRUCTURE | 12.97 kb 6 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
Map | cen - D12S2296 - D12S2347 - D12S2344 - D12S2271 - D12S2345 - D12S1857 - D12S2253 - D12S2264 - D12S861 - D12S1616 - D12S1340 - D12S2300 - OAS1 /D12S1960 /D12S2019 - (D12S2291 - D12S2247 ),OAS3 /D12S2397 - D12S2277 - OAS2 /D12S1895 /D12S1888 - D12S2293 - D12S2292 - D12S2295 - qter |
Authors | Renault (97) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | homomer , tetramer |
HOMOLOGY |
Homologene |
FAMILY | |
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CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | extracellular |
intracellular | |
intracellular,cytoplasm,organelle,mitochondria | |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,endoplasmic reticulum | |
intracellular,cytoplasm,cytosolic | |
intracellular,nucleus,nucleoplasm |
basic FUNCTION | |
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CELLULAR PROCESS | cell life, differentiation |
cell life, cell death/apoptosis | |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
nucleotide |
a component | components of the innate immune response to viruses |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
induced by | interferon induced |
ASSOCIATED DISORDERS |
corresponding disease(s) | PAPHG |
Susceptibility |
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Variant & Polymorphism SNP , other | |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |