basic FUNCTION
| is a G/T-mismatch DNA-binding protein and a deaminated DNA-binding protein |
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exhibits a periodic rise in its phosphorylation levels during the cell cycle, with hyperphosphorylation occurring in mitotic cells |
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participates in combinatorial transcriptional control with the AP-1 transcription factor |
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required for the efficient recruitment of AP-1 to chromatin |
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FOXK1 and/or FOXK2 are likely to act as important regulators that reprogram cellular metabolism to induce aerobic glycolysis |
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FOXK1, FOXK2 play a critical role in the control of apoptosis, metabolism and mitochondrial function |