SUBCELLULAR LOCALIZATION
| intracellular
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| intracellular,cytoplasm,organelle,membrane
|
| intracellular,cytoplasm,organelle,Golgi
|
| intracellular,nucleus,nucleoplasm
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text
| trans Golgi |
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GOLGA1, GOLGA4 are targeted to the Golgi membrane through their GRIP domains |
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ARFRP1 and GOLGA4 were detected in the same compartment close to the nucleus, presumably the trans-Golgi |
basic FUNCTION
| Golgi complex antigen targeted by autoantibodies associated with Sjogren syndrome |
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GOLGA1, GOLGA4, GCC1, GCC2 can self-associate to form homodimers exclusively |
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functions in Golgi positioning indirectly, probably by regulating retrograde movement of cargo required for recruitment or activation of dynein-dynactin complexes on newly formed Golgi elements |
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key regulator of TNF secretion and LPS activation of macrophages results in increased Golgi carriers for export |
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coiled-coil protein that recycles between the cytosol and buds/vesicles of the TGN and which plays a fundamental role in trafficking transport vesicles |