protein
| RNA polymerase 1 |
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both NOLC1 and TP53 work together synergistically to activate the MDM2 promoter in nasopharyngeal carcinoma (NPC) cells |
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transiently associates with the mature nucleolar H/ACA and C/D box small nucleolar ribonucleoproteins (snoRNPs) |
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highly phosphorylated protein inhibitor of casein kinase 2 (CSNK2A1, CSNK2B1) |
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CSNK2A1 activity is inhibited by NOLC1 and reactivated by GPRIN2 by competitive binding at the substrate recognition site of CSNK2A1 |
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rRNA gene chromatin (r-chromatin) association of NOLC1, DKC1, and FBL was dependent on the transcription factor upstream binding factor (UBF) |