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FLASH GENE
Symbol MS4A6A contributors: - updated : 24-02-2004
HGNC name membrane-spanning 4-domains, subfamily A, member 6A
HGNC id 13375
Location 11q12.1      Physical location : 59.939.080 - 59.950.674
Synonym symbol(s) CD20-L3,CDA01,MS4A6
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 10.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
text splice variants
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Digestiveliver    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticmonocyte
Lymphoid/ImmuneB cell
cell lineage
cell lines erythroleukemia cells
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
transmembrane (TM) protein comprising a short intracellular domain,four transmembrane segments (4TM) and a long cytoplasmic tail,involved in intracellular signaling
HOMOLOGY
Homologene
FAMILY membrane-spanning 4-domains,subfamily A
CATEGORY signaling , receptor membrane
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION involved in the regulation of B cell activation and proliferation
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS immunity/defense
PATHWAY
metabolism
signaling signal transduction
a component component of oligomeric cell surface complex involved in signal transduction
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS