Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol HAO2 contributors: npt/ - updated : 04-05-2004
HGNC name hydroxyacid oxidase 2 (long chain)
HGNC id 4810
Location 1p13.3-p13.2      Physical location : 119.911.401 - 119.936.751
Synonym name
  • (S)-2-hydroxy-acid oxidase
  • glycolate oxidase
  • long-chain L-2-hydroxy acid oxidase
  • growth-inhibiting protein 16
  • Synonym symbol(s) HAOX2, GIG16
    EC.number 1.1.3.15
    DNA
    TYPE functioning gene
    STRUCTURE 25.35 kb     9 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    text variants 1 and 2 encode the same protein
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1476 39 351 - -
    - - 1696 39 351 - -
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticthymus    
    Digestiveliver    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Lymphoid    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a C terminal consensus type 1 peroxisomal targeting signal (PTS1) serine-arginine leucine
  • HOMOLOGY
    Homologene
    FAMILY
  • FMN-dependent alpha-hydroxy acid dehydrogenase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,peroxisome
    basic FUNCTION
  • 2-hydroxyacid oxidase activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    highest activity toward 2 hydroxy-palmitate
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • FMN
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS