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FLASH GENE

Symbol

SLAMF1

contributors: mct - updated : 16-02-2017

HGNC name	signaling lymphocytic activation molecule family member 1
HGNC id	10903

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral       loss of function in Chronic lymphocytic leukemia (CLL) modulates genetic pathways that regulate chemotaxis and autophagy and that potentially affect drug responses constitutional     --over   significantly increased expression of SLAMF1 by CD3+CD4+ helper T cells and CD19+ B cells in patients with SLE and active disease

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	new diagnostic marker in CNS tumors
Therapy target
	System Type Disorder Pubmed cancer brain   potential target for novel therapeutic approaches in CNS tumors

ANIMAL & CELL MODELS