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FLASH GENE
Symbol IL1F7 contributors: mct - updated : 15-02-2012
HGNC name interleukin 1 family, member 7 (zeta)
HGNC id 15563
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a prodomain (15 to 30 AA),cleaved by CASP1
    • isoforms Precursor
    HOMOLOGY
    Homologene
    FAMILY
  • interleukin 1 family
    • CATEGORY signaling cytokine
    SUBCELLULAR LOCALIZATION extracellular
    text translocates to the nucleus after caspase-1 processing and may act as a transcriptional modulator reducing the production of LPS-stimulated proinflammatory cytokines
    basic FUNCTION
  • emerges as a natural suppressor of innate inflammatory and immune responses
  • may be an anti-inflammatory member of the IL1 family
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense , inflammation
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • DEFB103B up-regulated the mRNA and protein expression of IL1F7
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS