basic FUNCTION
| controling the expression of neural adhesion molecule during embryonic development of both the central and peripherical nervous system |
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involved in the differentiation of neuronal progenitors implicated in the pattern formation of human cerebral and cerebellar structures |
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plays an essential role in the migration and survival of cerebellar granule cells and precerebellar neurons |
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may be involved in the differentiation of the specific subsets of neuronal progenitors |
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play an essential role in maintaining inner ear hair cells, cerebellar granule cells, and precerebellar neurons |
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crucially required for the survival but not for the specification of zonal layer neurons in the superior colliculus |
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having regulatory sequences required for cell-specific gene expression and autoregulation in the inner ear and central nervous system |
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BARHL1, BARHL2 share a conserved function as cell type-specific regulators of Caspase3 activities |
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homeodomain transcription factor known to regulate migration and survival of granule cell precursors ( |
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important role in brain development, and potentially perturbations of thyroid hormone-mediated transcriptional control of BARHL1 may play a role in the impaired neurodevelopment induced by hypothyroidism |
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