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FLASH GENE
Symbol KLHL22 contributors: mct - updated : 03-09-2011
HGNC name kelch-like 22 (Drosophila)
HGNC id 25888
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland    
Nervousnerve    
Reproductivefemale systemovary   
 male systemprostate   
Respiratoryrespiratory tractlarynx   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one BTB(POZ) domain
  • six Kelch repeats
    • HOMOLOGY
    interspecies homolog to murine Klhl22 (94.3pc)
    Homologene
    FAMILY
    CATEGORY DNA associated
    SUBCELLULAR LOCALIZATION
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein KLHL21 and KLHL22, interact with CUL3 and are required for efficient chromosome alignment
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS