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| deletion of both Rac1 and Rac2 murine alleles leads to a massive egress of hematopoietic stem/progenitor cells (HSC/Ps) into the blood from the marrow  | |
mice with specific Rac1 deficiency in the B cell lineage display a completely blocked development of B cell |
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deletion of Rac1 in adult mouse epidermis stimulated stem cells to divide and undergo terminal differentiation, leading to failure to maintain the interfollicular epidermis, hair follicles, and sebaceous glands |
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temporally and specifically deleted Rac1 gene in adult mouse cardiomyocytes leads to decreased gp91(phox) and p67(phox) interaction, NADPH oxidase activity, and myocardial oxidative stress in response to angiotensin II stimulation |
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amount of Rac1 associating with beta4 integrin and the activity of both Rac1 and cofilin are significantly lower in BPAG1e-deficient keratinocyte cells |