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FLASH GENE
Symbol VPREB3 contributors: npt/ - updated : 14-03-2005
HGNC name pre-B lymphocyte gene 3
HGNC id 12710
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
2 - 602 13.58 123 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Lymphoid/Immunelymph node    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Lymphoid    
cell lineage cell lines representative of all stages of B-cell differentiation with the exception of plasmacytomas
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text liver, spleen, lymph node
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal signal peptide
  • three framework regions (FR) and three complementary regions in the order FR1 - CDR1 - FR2 - CDR2 - FR3 - CD3
  • HOMOLOGY
    interspecies homolog to murine 8hs20
    Homologene
    FAMILY
  • immunoglobulin superfamily
  • CATEGORY immunity/defense
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • maybe contributing to mu chain transport in pre-B cells
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS