Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

VPREB3

contributors: npt/ - updated : 14-03-2005

HGNC name	pre-B lymphocyte gene 3
HGNC id	12710

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	22q11.23      Physical location : 24.094.933 - 24.096.630
Synonym name	immunoglobulin pre B lymphocyte gene 3
	VpreB3 protein
Synonym symbol(s)	8HS20, N27C7-2

DNA

TYPE	functioning gene
STRUCTURE	1.66 kb     2 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

Map

see IGLL@

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed VPREB3 2 - 602 13.58 123 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol blood / hematopoietic spleen         Lymphoid/Immune lymph node

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic bone marrow       Lymphoid

cell lineage	cell lines representative of all stages of B-cell differentiation with the exception of plasmacytomas
cell lines
fluid/secretion

at STAGE

physiological period

fetal, pregnancy

Text	liver, spleen, lymph node

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a N terminal signal peptide
	three framework regions (FR) and three complementary regions in the order FR1 - CDR1 - FR2 - CDR2 - FR3 - CD3

HOMOLOGY

interspecies

homolog to murine 8hs20

Homologene

FAMILY

immunoglobulin superfamily

CATEGORY

immunity/defense

SUBCELLULAR LOCALIZATION

basic FUNCTION

maybe contributing to mu chain transport in pre-B cells

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS