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FLASH GENE
Symbol ADAM30 contributors: npt/ - updated : 10-02-2004
HGNC name ADAM metallopeptidase domain 30
HGNC id 208
Location 1p12-p11      Physical location : 120.436.156 - 120.439.113
Synonym name a disintegrin and metalloproteinase domain 30
Synonym symbol(s) svph4
EC.number 3.4.24.-
DNA
TYPE functioning gene
STRUCTURE 2.96 kb     1 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
text structure intronless
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2972 89 790 - Ceretti
- splicing 2350 - 781 testis Ceretti
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  specific
cell lineage spermatogenic cells
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • domains similar to hemorrhagic snake venom proteins (HSVP)
  • a Zn-binding site metalloproteinase
  • a disintegrin-like domain
  • a cysteine rich domain
  • an EGF-like repeat
  • a transmembrane domain
  • a cytoplasmic tail
  • conjugated GlycoP , MetalloP
    isoforms Precursor
    HOMOLOGY
    Homologene
    FAMILY
  • ADAM (a disintegrin and metalloprotease domain) family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • a disintegrin and metalloprotease, cell surface adhesion protein involved in spermatogenesis
  • CELLULAR PROCESS protein, post translation
    protein, degradation
    PHYSIOLOGICAL PROCESS reproduction/sex
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS