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FLASH GENE

Symbol

BARX2

contributors: mct - updated : 09-06-2012

HGNC name	BARX homeobox 2
HGNC id	956

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in ovarian cancer (suppressor of ovarian cancer progression )

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	Barx2(-/-) mice show defective lacrimal gland morphogenesis, absence of the harderian (HG), and meibomian (MG)] glands and eyelid fusion
	mice lacking the Barx2 gene show reduced postnatal muscle growth, muscle atrophy, and defective muscle repair