SUBCELLULAR LOCALIZATION
| intracellular
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| intracellular,cytoplasm,organelle,membrane
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| intracellular,cytoplasm,organelle,endoplasmic reticulum
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| intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
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| intracellular,cytoplasm,cytoskeleton,microtubule,mitotic spindle
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| intracellular,nucleus,chromatin/chromosome,centromere
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| intracellular,nucleus,chromatin/chromosome,kinetochore
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| moving from the centromere/kinetochore at prometaphase to kinetochore microtubules at metaphase and then back to the centromere/kinetochore at anaphase |
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kinetochore residency at prometaphase kinetochores is dependent on its interaction with ZWINT, and is essential for mitotic checkpoint arres (Famulski 2008) |
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located in the endoplasmic reticulum as well as in the cytosol during interphase (Hirose 2004) |
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ZWINT localizes to the kinetochore in prophase, before ZW10 localization, and remains at the kinetochore until anaphase, after ZW10 has dissociated |