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FLASH GENE

Symbol

PSMB10

contributors: mct - updated : 25-09-2024

HGNC name	proteasome (prosome, macropain) subunit, beta type, 10
HGNC id	9538

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

IMD121 , PRAAS5

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in hepatocellular carcinoma (HCC) tumoral     --over   in Kidney Renal Clear Cell Carcinoma when compared to normal tissues, negatively impacting patient prognosis

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed miscelleaneous hypertension   inhibition of PSMB10 may represent a potential therapeutic target for treating hypertensive atrial fibrillation (AF)

ANIMAL & CELL MODELS