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FLASH GENE

Symbol

TRPM5

contributors: mct - updated : 10-12-2014

HGNC name	transient receptor potential cation channel, subfamily M, member 5
HGNC id	14323

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	knockout of Trpm5 or Plcb2 selectively expressed in taste tissue, in mice abolished sweet, amino acid, and bitter taste reception, but did not affect sour or salty tastes
	increased plasma insulin levels downregulate Trpm5 expression in pancreatic islets from leptin-deficient mouse models of type 2 diabetes