Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

Home Page

FLASH GENE

Symbol

ASAH1

contributors: mct/pgu - updated : 03-07-2018

HGNC name	N-acylsphingosine amidohydrolase (acid ceramidase) 1
HGNC id	735

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

FLGD , SMAPME

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in prostate carcinoma

Susceptibility

to adult SMA phenotype with no myoclonic epilepsy

Variant & Polymorphism SNP	association between ASAH1 variants and an adult SMA phenotype with no myoclonic epilepsy nor death in early age

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer reproductive breast expression correlates with a better prognosis in ER-positive breast cancer cancer reproductive prostate critical regulator of prostate cancer progression by affecting tumor cell proliferation and migration and also responses to drug therapy, suggesting ASAH1 as a potential therapy target in advanced PCa

ANIMAL & CELL MODELS