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FLASH GENE
Symbol DRG1 contributors: - updated : 11-06-2004
HGNC name developmentally regulated GTP binding protein 1
HGNC id 3029
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cells
SystemCellPubmedSpeciesStageRna symbol
 epithelial cell
Cardiovascularendothelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Nedd3
Homologene
FAMILY NDRG gene family
CATEGORY regulatory , signaling
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm
basic FUNCTION a negative involment in the metastatic process in prostate cancer
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
  • GTP binding
  • binding to SCL in clones from human fetal liver and thymus
  • cell & other
    REGULATION
    induced by various chemical agents and antineoplastic drugs such as tunicamycin, mercaptoethanol and homocysteine
    Other developmentally regulated
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene metastasis suppressor gene for prostate cancer that may serve as an useful prognostic marker
    Marker
    Therapy target
    ANIMAL & CELL MODELS