Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

AKT3

contributors: mct - updated : 29-11-2014

HGNC name	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
HGNC id	393

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

DEL1Q44 , MPPH2

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in estrogen receptor-negative breast tumor tumoral       gain of function associated with the survival of melanoma cells

Susceptibility

Variant & Polymorphism

Candidate gene	for microcephaly and corpus callosum agenesis in 1qter microdeletion syndrome
Marker
Therapy target
	System Type Disorder Pubmed cancer brain glioma/neuroblstoma targeting AKT2 and AKT3 may hold promise for the treatment of patients with gliomas (PMID: 20167810)

ANIMAL & CELL MODELS